TPF Induction With Concomitant Chemoradiation to Treat Patients With Head and Neck Cancer

PHASE2UnknownINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

December 31, 2008

Primary Completion Date

April 30, 2012

Study Completion Date

April 30, 2012

Conditions
Head and Neck Cancer
Interventions
RADIATION

conventional radiotherapy with 'high' dose cisplatin

"radiotherapy: 5 fractions/week, total treatment time 7 weeks. Dose to gross tumor volume 70 Gy/35 fractions, dose to elective nodal areas 46 Gy/23 fractions.~100 mg/m2 cisplatin iv on day 1, 22 and 43"

RADIATION

accelerated radiotherapy with 'low' dose cisplatin

Accelerated radiotherapy 6 fractions/week, total treatment time 6 weeks. During one of the weekdays two fractions will be delivered with an interval of at least 6h. Dose to gross tumor volume 70 Gy/35 fractions, dose to elective nodal areas 46 Gy/23 fractions cisplatin 40 mg/m2 iv on day 1,8,18,22,29,35

Trial Locations (2)

Unknown

RECRUITING

Netherlands Cancer Institute, Amsterdam

6525 GH

RECRUITING

University Medical Center Nijmegen st Radboud, Nijmegen

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Sanofi

INDUSTRY

lead

Radboud University Medical Center

OTHER

NCT00774319 - TPF Induction With Concomitant Chemoradiation to Treat Patients With Head and Neck Cancer | Biotech Hunter | Biotech Hunter