526
Participants
Start Date
December 31, 2008
Primary Completion Date
May 31, 2010
Study Completion Date
December 31, 2010
Placebo (IP)
Induction phase (Week 0-8) (IP) - Placebo IV group
Ustekinumab 1mg/kg (IP)
Induction phase (Week 0-8) (IP) - Ustekinumab 1 mg/kg IV group
Ustekinumab 3 mg/kg (IP)
Induction phase (Week 0-8) (IP) - Ustekinumab 3mg/kg IV group
Ustekinumab 6 mg/kg (IP)
Induction phase (Week 0-8) (IP) - Ustekinumab 6mg/kg IV group
Placebo IV - Responder - Placebo SC (MP)
Maintenance phase (Week 8-36) (MP) - Receiving Placebo IV at Week 0 - Responder at week 6 - Receiving Placebo SC at Week 8 and Week 16
Placebo IV - Nonresponder - Ustekinumab 270/90 mg SC (MP)
Maintenance phase (Week 8-36) (MP) - Receiving Placebo IV at Week 0 - Nonresponder at week 6 - Receiving Ustekinumab 270 mg SC at Week 8 and 90 mg at Week 16
Ustekinumab IV - Responder - Placebo SC (MP)
Maintenance phase (Week 8-36) (MP) - Receiving Ustekinumab IV at Week 0 - Responder at week 6 - Receiving Placebo SC at Week 8 and Week 16
Ustekinumab IV - Responder - Ustekinumab 90mg SC (MP)
Maintenance phase (Week 8-36) (MP) - Receiving Ustekinumab IV at Week 0 - Responder at week 6 - Receiving Ustekinumab 90 mg SC at Week 8 and Week 16
Ustekinumab IV - Nonresponder - Placebo SC (MP)
Maintenance phase (Week 8-36) (MP) - Receiving Ustekinumab IV at Week 0 - Nonresponder at week 6 - Receiving Placebo SC at Week 8 and Week 16
Ustekinumab IV - Nonresponder - Ustekinumab 90mg SC (MP)
Maintenance phase (Week 8-36) (MP) - Receiving Ustekinumab IV at Week 0 - Nonresponder at week 6 - Receiving Ustekinumab 90 mg SC at Week 8 and Week 16
Mobile
Scottsdale
La Jolla
Los Angeles
Roseville
San Carlos
San Francisco
Englewood
Lakewood
Littleton
Hamden
Gainesville
Hollywood
Jacksonville
Miami
Naples
Panama City
Pembroke Pines
Port Charlotte
Port Orange
South Miami
Tampa
Vero Beach
Winter Park
Zephyrhills
Atlanta
Columbus
Decatur
Macon
Newnan
Arlington Heights
Chicago
Evanston
Indianapolis
Clive
Pratt
Lexington
Louisville
Baltimore
Chevy Chase
Towson
Boston
Burlington
Worcester
Ann Arbor
Chesterfield
Detroit
Troy
Rochester
Ocean Springs
Mexico
Lebanon
Egg Harbor
Great Neck
New York
Poughkeepsie
Setauket
Stony Brook
Chapel Hill
Charlotte
Greenville
Kinston
New Bern
Raleigh
Beavercreek
Cincinnati
Cleveland
Dayton
Oklahoma City
Philadelphia
Charleston
Columbia
Chattanooga
Nashville
Austin
Houston
Lewisville
San Antonio
Ogden
Salt Lake City
Burlington
Charlottesville
Norfolk
Bellevue
Lakewood
Seattle
Tacoma
Madison
Adelaide
Bankstown
Bedford Park
Box Hill
Concord
East Melbourne
Fitzroy
Frankston
Fremantle
Garran
Herston
Parkville
Prahran
South Brisbane
Innsbruck
Linz
Salzburg
Vienna
Bonheiden
Brussels
Edegem
Kortrijk
Leuven
Liège
Roeselare
Calgary
Edmonton
Vancouver
Victoria
Hamilton
London
Toronto
Montreal
Québec
Saskatoon
Amiens Cedex 1 80
Grenoble
Lille
Nice
Paris
Pessac
Rouen
Toulouse Cedex 9 N/A
Berlin
Hamburg
Hanover
Kiel
Leipzig
Lÿneburg
Markkleeberg
Minden
München
Münster
Regensburg
Afula
Beersheba
Haifa
Jerusalem
Kfar Saba
Petah Tikva
Tel Aviv
Amersfoort
Amsterdam
Leiden
Maastricht
Rotterdam
Auckland
Christchurch
Barcelona
Córdoba
León
Madrid
Oviedo
Palma
Sabadell
Zaragoza
Bristol
Cambridge
Coventry
Edinburgh
Harrow
London
Manchester
Newcastle upon Tyne
Norwich
Nottinghamshirecc
Lead Sponsor
Centocor, Inc.
INDUSTRY