Ridaforolimus in Treating Patients With Recurrent Metastatic and/or Locally Advanced Endometrial Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

November 13, 2008

Primary Completion Date

March 19, 2012

Study Completion Date

February 13, 2015

Conditions
Endometrial Cancer
Interventions
DRUG

ridaforolimus

oral ridaforolimus 40 mg days 1-5 each week (once daily for 5 consecutive days every week; cycle arbitrarily defined as a 4 week period)

GENETIC

gene expression analysis

OTHER

immunohistochemistry staining method

OTHER

laboratory biomarker analysis

Trial Locations (11)

T2N 4N2

Tom Baker Cancer Centre, Calgary

T6G 1Z2

Cross Cancer Institute, Edmonton

V1Y 5L3

BCCA - Cancer Centre for the Southern Interior, Kelowna

V3V 1Z2

BCCA - Fraser Valley Cancer Centre, Surrey

L8V 5C2

Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton

K7L 5P9

Cancer Centre of Southeastern Ontario at Kingston, Kingston

N6A 4L6

London Regional Cancer Program, London

M5G 2M9

Univ. Health Network-Princess Margaret Hospital, Toronto

H2L 4M1

CHUM - Hopital Notre-Dame, Montreal

H2W 1S6

McGill University - Dept. Oncology, Montreal

S4T 7T1

Allan Blair Cancer Centre, Regina

Sponsors
All Listed Sponsors
collaborator

Ariad Pharmaceuticals

INDUSTRY

lead

NCIC Clinical Trials Group

NETWORK