Evaluation Of The Efficacy Of The Combination Of Axitinib With Pemetrexed And Cisplatin In The Treatment Of Non-Squamous Non-Small Cell Lung Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

January 31, 2009

Primary Completion Date

March 31, 2011

Study Completion Date

March 31, 2012

Conditions
Carcinoma, Non-Small Cell Lung
Interventions
DRUG

axitinib

5mg BID po up to max 10mg BID po

DRUG

axitinib

5mg BID po up to max 10mg BID po paused for 3 days before each cycle of concomitant chemotherapy

DRUG

chemotherapy

Pemetrexed(500mg/m2)/Cisplatin(75mg/m2) x max 6 cycles

DRUG

axitinib

5mg BID po up to max 10mg BID po paused before each concomitant chemotherapy

DRUG

chemotherapy

Pemetrexed(500mg/m2)/Cisplatin(75mg/m2) x max 6 cycles

Trial Locations (52)

100

Pfizer Investigational Site, Taipei

112

Pfizer Investigational Site, Taipei

402

Pfizer Investigational Site, Taichung

10043

Pfizer Investigational Site, Orbassano (TO)

12002

Pfizer Investigational Site, Castellon

16132

Pfizer Investigational Site, Genova

19611

Pfizer Investigational Site, West Reading

28007

Pfizer Investigational Site, Madrid

28041

Pfizer Investigational Site, Madrid

30033

Pfizer Investigational Site, Decatur

30060

Pfizer Investigational Site, Marietta

30341

Pfizer Investigational Site, Atlanta

30342

Pfizer Investigational Site, Sandy Springs

31217

Pfizer Investigational Site, Macon

35805

Pfizer Investigational Site, Huntsville

40705

Pfizer Investigational Site, Taichung

41009

Pfizer Investigational Site, Seville

49102

Pfizer Investigational Site, Dnipropetrovsk

55043

Pfizer Investigational Site, Lido Di Camaiore (LU)

61615

Pfizer Investigational Site, Peoria

61701

Pfizer Investigational Site, Bloomington

115478

Pfizer Investigational Site, Moscow

194044

Pfizer Investigational Site, Saint Petersburg

197089

Pfizer Investigational Site, Saint Petersburg

357502

Pfizer Investigational Site, Pyatigorsk

600114

Pfizer Investigational Site, Bacau

700106

Pfizer Investigational Site, Iași

17033-0850

Pfizer Investigational Site, Hershey

02914

Pfizer Investigational Site, East Providence

02915

Pfizer Investigational Site, East Providence

Unknown

Pfizer Investigational Site, Sunto-gun

59-300

Pfizer Investigational Site, Lubin

05-400

Pfizer Investigational Site, Otwock

64-920

Pfizer Investigational Site, Piła

60-569

Pfizer Investigational Site, Poznan

61-485

Pfizer Investigational Site, Poznan

82-550

Pfizer Investigational Site, Prabuty

00-909

Pfizer Investigational Site, Warsaw

08221

Pfizer Investigational Site, Terrassa

07010

Pfizer Investigational Site, Palma de Mallorca

CH-4016

Pfizer Investigational Site, Basel

CH-4031

Pfizer Investigational Site, Basel

CH-4101

Pfizer Investigational Site, Bruderholz

CH-4410

Pfizer Investigational Site, Liestal

03115

Pfizer Investigational Site, Kyiv

RM7 0AG

Pfizer Investigational Site, Romford

HA6 2RN

Pfizer Investigational Site, Northwood

Pfizer Investigational Site, Middlesex

BH7 7DW

Pfizer Investigational Site, Bournemouth

BN2 5BE

Pfizer Investigational Site, Brighton

DD1 9SY

Pfizer Investigational Site, Dundee

BH15 2JB

Pfizer Investigational Site, Poole

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT00768755 - Evaluation Of The Efficacy Of The Combination Of Axitinib With Pemetrexed And Cisplatin In The Treatment Of Non-Squamous Non-Small Cell Lung Cancer | Biotech Hunter | Biotech Hunter