Endoscopic Variceal Ligation (EVL)+ Drugs Versus Endoscopic Variceal Ligation (EVL) Alone For Secondary Prophylaxis

NACompletedINTERVENTIONAL
Enrollment

177

Participants

Timeline

Start Date

October 31, 2002

Primary Completion Date

December 31, 2006

Study Completion Date

June 30, 2007

Conditions
Portal Hypertension
Interventions
DRUG

EVL + Propranolol + Isosorbide 5 mononitrate

Treatment was started with propranolol at a dose of 40 mg twice a day. The heart rate and blood pressure were checked after 12 to 24 hours. The dose of propranolol was increased at increments of 20 to 40 mg per day until the patient achieved a heart rate of 55 bpm, or a maximum dose of 320 mg/day was achieved.ISMN was added at a dose of 10 mg twice a day. The dose was escalated at increments of 10-20 mg/day till a maximum dose of 40 mg/day was reached.

OTHER

EVL alone

Trial Locations (1)

110002

Department of Gastroenterology, G B Pant Hospital, New Delhi

All Listed Sponsors
lead

Govind Ballabh Pant Hospital

OTHER_GOV

NCT00766805 - Endoscopic Variceal Ligation (EVL)+ Drugs Versus Endoscopic Variceal Ligation (EVL) Alone For Secondary Prophylaxis | Biotech Hunter | Biotech Hunter