Blood Pressure Lowering of Aliskiren HCTZ Compared to HCTZ in Stage 2 Systolic Hypertension in Older Population

PHASE4CompletedINTERVENTIONAL

Enrollment

451

Participants

Timeline

Start Date

September 30, 2008

Primary Completion Date

April 30, 2009

Study Completion Date

April 30, 2009

Conditions

Hypertension

Interventions

DRUG

Aliskiren

Aliskiren 150 mg for 1 week, Aliskiren 300 mg (with or without amlodipine)for 7 weeks

DRUG

Hydrochlorothiazide

Hydrochlorothiazide (HCTZ) 12.5 mg for week 1; Hydrochlorothiazide (HCTZ) 25 mg (with or without amlodipine)for 7 weeks

Trial Locations (1)

Sites in USA, East Hanover