Panitumumab, Docetaxel, Cisplatin, Radiation Therapy, and Surgery in Treating Patients With Newly Diagnosed, Locally Advanced Esophageal Cancer or Cancer of the Gastroesophageal Junction

PHASE2CompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

January 31, 2009

Primary Completion Date

November 30, 2011

Study Completion Date

December 31, 2014

Conditions
Adenocarcinoma of the Gastroesophageal JunctionEsophageal Cancer
Interventions
BIOLOGICAL

panitumumab

DRUG

cisplatin

DRUG

docetaxel

PROCEDURE

neoadjuvant therapy

PROCEDURE

therapeutic conventional surgery

RADIATION

radiation therapy

Trial Locations (21)

15212

Allegheny Cancer Center at Allegheny General Hospital, Pittsburgh

15232

UPMC Cancer Centers, Pittsburgh

29425

Hollings Cancer Center at Medical University of South Carolina, Charleston

45331

Wayne Hospital, Greenville

45406

Good Samaritan Hospital, Dayton

45429

Charles F. Kettering Memorial Hospital, Kettering

48073

William Beaumont Hospital - Royal Oak Campus, Royal Oak

55905

Mayo Clinic Cancer Center, Rochester

63110

Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis, St Louis

97227

Legacy Emanuel Hospital and Health Center and Children's Hospital, Portland

31403-3089

Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center, Savannah

60611-3013

Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago

60637-1470

University of Chicago Cancer Research Center, Chicago

60201-1781

Evanston Hospital, Evanston

62794-9677

Simmons Cooper Cancer Institute, Springfield

40503-9985

Central Baptist Hospital, Lexington

03756-0002

Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon

28232-2861

Blumenthal Cancer Center at Carolinas Medical Center, Charlotte

27157-1096

Wake Forest University Comprehensive Cancer Center, Winston-Salem

97213-2967

Providence Cancer Center at Providence Portland Medical Center, Portland

17822-0001

Geisinger Cancer Institute at Geisinger Health, Danville

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

Amgen

INDUSTRY

lead

Alliance for Clinical Trials in Oncology

OTHER