Irinotecan/Cetuximab Followed by XELOX/Cetuximab vs the Reverse Sequence in Metastatic CRC

PHASE2TerminatedINTERVENTIONAL
Enrollment

68

Participants

Timeline

Start Date

November 30, 2008

Primary Completion Date

November 30, 2008

Study Completion Date

November 30, 2008

Conditions
Colorectal Cancer
Interventions
DRUG

Irinotecan

Irinotecan (IV) 150 mg/m2 on day 1 every two weeks until progression

DRUG

Capecitabine

Capecitabine (p.o) 2000 mg/m2 (1000 mg/m2 x 2) on day 1-7 every 2 weeks until progression

DRUG

Cetuximab

Cetuximab(IV) 500 mg/m2 on day 1 every two weeks until progression

DRUG

Oxaliplatin

Oxaliplatin (I.V) 85 mg/m2 on day 1 every two weeks until progression

Trial Locations (10)

Unknown

University Hospital of Heraklion, Dep of Medical Oncology, Heraklion

University General Hospital of Alexandroupolis, Dep of Medical Oncology, Alexandroupoli

"Laikon General Hospital, Medical Oncology Unit, Propedeutic Dep of Internal Medicine", Athens

401 Military Hospital of Athens, Athens

Air Forces Military Hospital of Athens, Athens

"IASO General Hospital of Athens, 1st Dep of Medical Oncology", Athens

State General Hospital of Larissa, Larissa

"Metaxa's Anticancer Hospital of Piraeus, 1st Dep of Medical Oncology", Piraeus

"Theagenion Anticancer Hospital of Thessaloniki, 2nd Dep of Medical Oncology", Thessaloniki

Interbalkan Hospital, division of Oncology, Pylaia, Thessaloniki, Thessaloniki

All Listed Sponsors
collaborator

University Hospital of Crete

OTHER

lead

Hellenic Oncology Research Group

OTHER