Cardiovascular Study of Lisdexamfetamine in Healthy and Hypertensive Attention Deficit Hyperactivity Disorder Adults

PHASE4CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

April 30, 2008

Primary Completion Date

March 31, 2011

Study Completion Date

March 31, 2011

Conditions
Attention Deficit Hyperactivity Disorder (ADHD)
Interventions
DRUG

Lisdexamfetamine

Lisdexamfetamine daily until the completion of participation in the clinical trial (up to Week 11 or final study visit). Subjects will start on 30 mg of LDX per day for the first week of treatment. The dose will be increased weekly in 20 mg increments, up to a 70 mg daily (maximum). If significant adverse effects (AE) occur, the daily dose may be reduced by 20 mg. At subsequent visits, a higher dose may be resumed if tolerated. Both cohorts of the study will follow the same treatment plan.

Trial Locations (1)

02138

Massachusetts General Hospital, Cambridge

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Shire

INDUSTRY

lead

Massachusetts General Hospital

OTHER