Study of the Effect of Rifampicin on the Pharmacokinetics (PK) of Multiple Doses of Cediranib in Patients With Solid Tumours

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

September 9, 2008

Primary Completion Date

July 30, 2009

Study Completion Date

December 31, 2025

Conditions
Solid Tumors
Interventions
DRUG

cediranib

45 mg cediranib once daily from Days 1-7; cediranib 45 mg plus 600 mg rifampicin from Days 8-14; 45 mg cediranib once daily from Days 15-28; from Day 29 patients may continue on 45 mg cediranib or dose reduce.

Trial Locations (6)

T6G 1Z2

Research Site, Edmonton

H3T 1E2

Research Site, Montreal

DD1 9SY

Research Site, Dundee

G12 0YN

Research Site, Glasgow

NW1 2PG

Research Site, London

SE1 9RT

Research Site, London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY