300
Participants
Start Date
February 28, 2009
Primary Completion Date
November 30, 2009
Study Completion Date
November 30, 2009
Nicotine Gum
2 mg or 4 mg for 12 week treatments and followed by 12 week off-treatment follow-up. Recommend subject to use 8-12 pieces daily for first 8 weeks and 4-6 pieces daily the next 2 weeks, then reduce to 1-3 pieces each day in last 2 weeks
Nicotine Patch
Each will use 15 mg/16 h patch for the first 8 weeks, 10 mg/16 h for the following 2 weeks and 5 mg/16 h for the last 2 weeks. Then followed by 12 week off-treatment follow-up.
Beijing ChaoYang Hospital, Beijing
People's Hospital affiliated to Beijing University, Beijing
Chang Zheng Hospital, Shanghai
Zhong Shan Hospital affiliated to Fudan University, Shanghai
No. 1 Hospital affiliated to Zhongshan University, Guangzhou
No. 1 Hospital affiliated to Guangzhou Medical University, Guangzhou
Lead Sponsor
McNeil AB
INDUSTRY