Multi-Centre, Open-Label, Two Segment, Study Comparing Plasma Pharmacokinetics of Ketoprofen in Diractin® Alone to Diractin® Applied Concomitant With Heat or Moderate Exercise

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

October 31, 2007

Primary Completion Date

March 31, 2008

Study Completion Date

May 31, 2008

Conditions

Pharmacokinetic

Interventions

DRUG

Diractin

100 mg Ketoprofen to 2 joints

DRUG

Diractin

400 mg ketoprofen to 4 joints

DRUG

Diractin

100 and 400 mg Ketoprofen used concomittant with heat

DRUG

Diractin

100 and 400 mg Ketoprofen concomittant with moderate exercise

Trial Locations (2)

X-pert Med GmbH, Jena

ClinPharm Interantional GmbH, Leipzig