Evaluation of the Efficacy of Varenicline on Cognition, Safety, Tolerability and Pharmacokinetics in Subjects With Mild-to-Moderate Alzheimer's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

July 31, 2009

Primary Completion Date

November 30, 2010

Study Completion Date

November 30, 2010

Conditions
Alzheimer's Disease
Interventions
DRUG

Varenicline

0.5 mg once daily for 1 week followed by 0.5 mg twice daily for 1 week followed by 1 mg twice daily for 4 weeks

DRUG

Placebo

Placebo once daily for 1 week followed by placebo twice daily for 5 weeks.

Trial Locations (8)

463-707

Pfizer Investigational Site, Seongnam

602-715

Pfizer Investigational Site, Busan

700-721

Pfizer Investigational Site, Daegu

400-711

Pfizer Investigational Site, Incheon

136-705

Pfizer Investigational Site, Seoul

138-736

Pfizer Investigational Site, Seoul

158-710

Pfizer Investigational Site, Seoul

443-721

Pfizer Investigational Site, Suwon

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY