Beta Cell Rescue in New Onset Type 1 Diabetes With Efalizumab

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

October 31, 2008

Primary Completion Date

November 30, 2009

Study Completion Date

November 30, 2009

Conditions
Diabetes Mellitus, Type 1
Interventions
DRUG

efalizumab

Enrollees randomized to efalizumab will receive the first dose of 0.7mg/kg subcutaneously given at enrollment, and 1.0 mg/kg subcutaneously weekly for 26 weeks self or family-administered after injection training. This is the FDA-approved initial and subsequent doses of efalizumab used for psoriasis treatment

DRUG

placebo

Enrollees receiving placebo will be given a subcutaneous injection of equal volume and appearance to treatment on the same schedule.

All Listed Sponsors
collaborator

Juvenile Diabetes Research Foundation

OTHER

collaborator

Genentech, Inc.

INDUSTRY

lead

Emory University

OTHER