Attention Deficit Hyperactivity Disorder (ADHD) Smoking Cessation Study

NACompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

December 31, 2007

Primary Completion Date

July 31, 2011

Study Completion Date

July 31, 2011

Conditions
Attention Deficit Hyperactivity DisorderNicotine Dependence
Interventions
DRUG

Transdermal Nicotine Patch

All subjects will lreceive transdermal nicotine patch during beginning at Visit 0 (quit smoke date). The dose will be tapered down from 21 mg to 14mg after week 1,vthen to 7 mg after week 2. Subjects will remain at 7mg until the 4th week.

DRUG

Lis-dexamphetamine (Vyvanse)

Subjects on this arm will receive Lis-dexamphetamine day after the identified quit date. All subject will start with 30mg once a day and will be titrated up to 50mg then to 70mg over a 3 week period to reach an optimized dose. They will then be maintained on this optimized dose until the 4th week.

DRUG

Placebo

Subjects on this arm will receive matching placebo, along with Nicotine Replacement Therapy.

Trial Locations (1)

27705

Duke Attention Deficit Hyperactivity Disorder (ADHD) Program, Durham

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Shire

INDUSTRY

lead

Duke University

OTHER

NCT00736255 - Attention Deficit Hyperactivity Disorder (ADHD) Smoking Cessation Study | Biotech Hunter | Biotech Hunter