32
Participants
Start Date
December 31, 2007
Primary Completion Date
July 31, 2011
Study Completion Date
July 31, 2011
Transdermal Nicotine Patch
All subjects will lreceive transdermal nicotine patch during beginning at Visit 0 (quit smoke date). The dose will be tapered down from 21 mg to 14mg after week 1,vthen to 7 mg after week 2. Subjects will remain at 7mg until the 4th week.
Lis-dexamphetamine (Vyvanse)
Subjects on this arm will receive Lis-dexamphetamine day after the identified quit date. All subject will start with 30mg once a day and will be titrated up to 50mg then to 70mg over a 3 week period to reach an optimized dose. They will then be maintained on this optimized dose until the 4th week.
Placebo
Subjects on this arm will receive matching placebo, along with Nicotine Replacement Therapy.
Duke Attention Deficit Hyperactivity Disorder (ADHD) Program, Durham
Lead Sponsor
Collaborators (1)
Shire
INDUSTRY
Duke University
OTHER