Maraviroc as an Immunomodulatory Drug for Antiretroviral-treated HIV Infected Patients Exhibiting Immunologic Failure

PHASE4CompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

September 30, 2008

Primary Completion Date

April 30, 2010

Study Completion Date

July 31, 2010

Conditions
HIV Infection
Interventions
DRUG

Placebo

Dose based on current medications in regimen: 150mg PO BID for those on a protease inhibitor-based regimen other than Tipranavir; 600mg PO BID for efavirenz-containing regimens; or 300 mg PO BID for all other regimens.

DRUG

Maraviroc

Dose based on current medications in regimen: 150mg orally (PO) twice daily (BID) for those on a protease inhibitor-based regimen other than Tipranavir; 600mg PO BID for efavirenz-containing regimens; or 300 mg PO BID for all other regimens.

Trial Locations (4)

44106

Case Western Reserve University, Cleveland

60612

Rush University - Stroger Hospital of Cook County, Chicago

94110

University of California San Francisco - San Francisco General Hospital, San Francisco

94305

Stanford University, Stanford

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

collaborator

amfAR, The Foundation for AIDS Research

OTHER

collaborator

Stanford University

OTHER

collaborator

Case Western Reserve University

OTHER

collaborator

Rush University

OTHER

lead

University of California, San Francisco

OTHER