Aprepitant With Dexamethasone Versus Ondansetron With Dexamethasone for PONV Prophylaxis in Patients Having Craniotomy

PHASE4CompletedINTERVENTIONAL
Enrollment

115

Participants

Timeline

Start Date

September 30, 2007

Primary Completion Date

June 30, 2009

Study Completion Date

June 30, 2009

Conditions
Postoperative Nausea and Vomiting
Interventions
DRUG

Aprepitant + Dexamethasone

Aprepitant 40 mg + Dexamethasone 10 mg

DRUG

Ondansetron + Dexamethasone

Ondansetron 4 mg + Dexamethasone 10 mg

Trial Locations (1)

27710

Duke University Medical Center, Durham

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Duke University

OTHER

NCT00734929 - Aprepitant With Dexamethasone Versus Ondansetron With Dexamethasone for PONV Prophylaxis in Patients Having Craniotomy | Biotech Hunter | Biotech Hunter