NCT00734435View on ClinicalTrials.gov

Olanzapine Given in Combination With Zonisamide SR to Prevent Weight Gain in Schizophrenic Subjects

PHASE2TerminatedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

September 30, 2008

Primary Completion Date

December 31, 2008

Study Completion Date

December 31, 2008

Conditions
SchizophreniaSchizoaffective DisorderSchizophreniform Disorder
Interventions
DRUG

zonisamide SR plus olanzapine

zonisamide SR 90 mg given twice daily and olanzapine 10 mg to 20 mg daily for 10 weeks (maintenance period)

DRUG

Placebo plus olanzapine

Placebo given twice daily and olanzapine 10-20 mg for 10 weeks (maintenance period)

Trial Locations (9)

11223

Brooklyn Medical Institute, Brooklyn

30308

Atlanta Center for Medical Research, Atlanta

34208

Florida Clincal Research Center, Bradenton

Florida Clinical Research Center, Maitland

46222

Larue D. Carter Hospital, Indianapolis

60523

American Medical Research, Oak Brook

91950

Synergy Research, National City

92126

CNRI San Diego, San Diego

92868

UCI Medical Center, Orange

Sponsors
All Listed Sponsors
lead

Orexigen Therapeutics, Inc

INDUSTRY