The Safety and Efficacy of Sublingual/Oral Immunotherapy for the Treatment of Milk Protein Allergy

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

August 31, 2008

Primary Completion Date

June 30, 2010

Study Completion Date

June 30, 2012

Conditions
Milk Allergy
Interventions
DRUG

Milk Protein Extract Immunotherapy goal of 4mg/day

Sublingual extract given daily in escalating doses with goal of 4 mg/day for approximately 20 weeks.

DRUG

Milk Protein Extract Immunotherapy goal of 7mg/day

Sublingual extract daily in escalating doses to goal of 7mg/day for approximately 1 1/2 years.

DRUG

Milk Powder Immunotherapy goal dose 2000 mg/day

Milk powder given orally in escalating doses with a goal dose of 2000mg/day given for approximately 1 1/2 years.

DRUG

Milk Powder Immunotherapy goal dose 1000mg/day

Milk powder given orally in escalating doses with a goal of 1000mg/day for approximately 1 1/2 years.

Trial Locations (2)

21287

Johns Hopkins Hospital, Baltimore

27710

Duke University, Durham

Sponsors
All Listed Sponsors
collaborator

Duke University

OTHER

collaborator

Greer Laboratories

INDUSTRY

lead

Johns Hopkins University

OTHER

NCT00732654 - The Safety and Efficacy of Sublingual/Oral Immunotherapy for the Treatment of Milk Protein Allergy | Biotech Hunter | Biotech Hunter