PREVENTKD (Prevent Risks by Early interVEntion at Nighttime in Type 1 Diabetes for Kidney Disease)

PHASE3TerminatedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

July 31, 2008

Primary Completion Date

June 30, 2010

Study Completion Date

June 30, 2010

Conditions
Type 1 Diabetes
Interventions
DRUG

Ramipril

"ACE inhibitor known as Ramipril~Subjects with nighttime blood pressure that does not drop during the night (non-dippers) maybe randomized into this group and given an ACE inhibitor (study medication). Therefore, the Non-Dippers groups II and III will be randomized to receive either drug or placebo."

DRUG

Placebo

Dippers (category of subjects with a nighttime dip in blood pressure) will all be given Placebo. Control group.

DRUG

Placebo

"Subjects with nighttime blood pressure that does not drop during the night (non-dippers) maybe randomized into the control group and given Placebo."

Trial Locations (6)

32611

University of Florida, Gainesville

60153

Loyola University Chicago, Maywood

60611

Northwestern University Feinberg School of Medicine, Chicago

60612

Rush University Medical Center, Endocrinology Section, Chicago

University of Illinois at Chicago, Chicago

60637

University of Chicago, Chicago

Sponsors
All Listed Sponsors
collaborator

Juvenile Diabetes Research Foundation

OTHER

collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

Northwestern University

OTHER