Examination of the Safety and Tolerability of NNC 0070-0002-0349 in Overweight/Obese Volunteers

PHASE1WithdrawnINTERVENTIONAL
0
Timeline

Start Date

July 31, 2008

Primary Completion Date

December 31, 2009

Study Completion Date

December 31, 2009

Conditions
Metabolism and Nutrition DisorderObesity
Interventions
DRUG

NNC 0070-0002-0349

Dose level 1: (6 subjects active, 2 subjects placebo). Subjects administered NNC 0070-0002-0349 will receive a subcutaneous injection. Subjects in the first 3 dose groups will receive two injections: one of randomized treatment (drug or placebo) and placebo

DRUG

NNC 0070-0002-0349

Dose level 2: (6 subjects active, 2 subjects placebo). Subjects administered NNC 0070-0002-0349 will receive a subcutaneous injection. Subjects in the first 3 dose groups will receive two injections: one of randomized treatment (drug or placebo) and placebo

DRUG

NNC 0070-0002-0349

Dose level 3: (6 subjects active, 2 subjects placebo). Subjects administered NNC 0070-0002-0349 will receive a subcutaneous injection. Subjects in the first 3 dose groups will receive two injections: one of randomized treatment (drug or placebo) and placebo

DRUG

NNC 0070-0002-0349

Dose level 4 for s.c. injection (6 subjects active, 2 subjects placebo)

DRUG

NNC 0070-0002-0349

Dose level 5 for s.c. injection (6 subjects active, 2 subjects placebo)

DRUG

placebo

Dose level 1: NNC 0070-0002-0349 placebo. Subjects administered placebo will receive a subcutaneous injection. Subjects in the first 3 dose groups will receive two injections: one of randomized treatment (drug or placebo) and placebo

DRUG

placebo

Dose level 2: NNC 0070-0002-0349 placebo. Subjects administered placebo will receive a subcutaneous injection. Subjects in the first 3 dose groups will receive two injections: one of randomized treatment (drug or placebo) and placebo

DRUG

placebo

Dose level 3: NNC 0070-0002-0349 placebo. Subjects administered placebo will receive a subcutaneous injection. Subjects in the first 3 dose groups will receive two injections: one of randomized treatment (drug or placebo) and placebo

DRUG

placebo

Dose level 4: NNC 0070-0002-0349 placebo for s.c. injection

DRUG

placebo

Dose level 5: NNC 0070-0002-0349 placebo for s.c. injection

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Novo Nordisk A/S

INDUSTRY