NCT00726726 - Drug Interaction Study With a Potential Alzheimer's Disease Compound | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

August 31, 2008

Primary Completion Date

October 31, 2008

Study Completion Date

October 31, 2008

Conditions

Alzheimer Disease

Interventions

DRUG

Interacting drugs - Cooperstown Cocktail (midazolam, warfarin, (+ vitamin K), caffeine, omeprazole and dextromethorphan)

Capsules + Tablets + Oral solution, Oral, Midazolam: 5 mg, Warfarin: 10 mg (vitamin K 10 mg), caffeine: 200 mg, omeprazole: 40 mg, dextromethorphan: 30 mg once daily, Day 1, 1 Day

DRUG

BMS-708163

Capsules, Oral, 150 mg, once daily, days 6-15, 10 Days

DRUG

BMS-708163 + Cooperstown Cocktail

Capsules + tablets + Oral solution, Oral, BMS-708163: 150 mg + Midazolam: 5 mg, Warfarin: 10 mg (vitamin K 10 mg), caffeine: 200 mg, omeprazole: 40 mg, dextromethorphan: 30 mg, BMS-708163, once daily, days 16-20 midazolam,warfarin, (+ vitamin K), caffeine, omeprazole and dextromethorphan once daily on Day 16, 5 Days

Trial Locations (1)

08690

Bristol-Myers Squibb Clinical Pharmacology Unit, Hamilton