Administration of Allogenic Red Blood Cells Loaded L-asparaginase in Cases of Relapse of Acute Lymphoblastic Leukaemia

PHASE1/PHASE2CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

August 31, 2008

Study Completion Date

March 31, 2009

Conditions

Acute Lymphoblastic Leukemia

Interventions

BIOLOGICAL

GRASPA

50 UI/Kg

BIOLOGICAL

GRASPA

100 UI/Kg

BIOLOGICAL

GRASPA

150 UI/Kg

DRUG

native L asparaginase

10000UI/m2, 14 infusions during 4 chemotherapy cycle

Trial Locations (1)

Hopital Debrousse, Lyon