Multiple IV Dose Study Of PF-04360365 In Patients With Mild To Moderate Alzheimer's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

198

Participants

Timeline

Start Date

December 5, 2008

Primary Completion Date

August 16, 2011

Study Completion Date

August 16, 2011

Conditions
Alzheimer's Disease
Interventions
BIOLOGICAL

PF-04360365 0.1 mg/kg

0.1 mg/kg every 60 days (10 doses total)

BIOLOGICAL

PF-04360365 0.5 mg/kg

0.5 mg/kg every 60 days (10 doses total)

BIOLOGICAL

PF-04360365 1 mg/kg

1 mg/kg every 60 days (10 doses total)

DRUG

Placebo

Placebo every 60 days (10 doses total)

BIOLOGICAL

PF-04360365 3 mg/kg

3 mg/kg every 60 days (10 doses total)

BIOLOGICAL

PF-04360365 8.5 mg/kg

8.5 mg/kg every 60 days (10 doses total)

Trial Locations (42)

1090

UZ Brussel / Geriatrie, Jette

2020

ZNA Middelheim / Neurology, Antwerp

2650

UZ Antwerpen, Department of Neurology, Edegem

3000

U.Z. Gasthuisberg / Neurologie, Leuven

3084

Heidelberg Repatriation Hospital, Austin Health, Heidelberg West

5000

Royal Adelaide Hospital, Adelaide

5011

The Queen Elizabeth Hospital and Health Service, Woodville South

6009

The McCusker Foundation for Alzheimer's Disease Research, Nedlands

33143

Miami Research Associates, South Miami

MRA Clinical Research, South Miami

Sleep Florida, LLC, South Miami

33176

Neuroscience Consultants, LLC, Miami

60007

Alexian Brothers Medical Center, Elk Grove Village

Alexian Brothers Neurosciences Institute, Elk Grove Village

66209

Stark Pharmacy, Overland Park

66211

Vince and Associates Clinical Research, Overland Park

66212

Vince and Associates Clinical Research, Overland Park

85013

Dedicated Phase 1, Phoenix

85381

Pivotal Research Center, Peoria

Sun Radiology- for MRI, Peoria

07724

Memory Enhancement Center of America, Inc, Eatontown

07755

Central Jersey Radiology, Oakhurst

02906

Butler Hospital, Providence

V6T 2B5

University of British Columbia Hospital, Division of Neurology, Vancouver

N6C 5J1

Parkwood Hospital, Geriatric Medicine, London

K9H 2P4

Kawartha Regional Memory Clinic, Peterborough

M3B 2S7

Toronto Memory Program, Toronto

M4N 3M5

Sunnybrook Health Sciences Centre, Toronto

H1T 2M4

Recherche Clinique de Neurologie, Montreal

J1H 1Z1

Diex Recherche Inc., Sherbrooke

463-707

Seoul National University Bundang Hospital, Seongnam-si

133-792

Hanyang University Hospital, Seoul

135-710

Samsung Medical Center, Seoul

136-705

Korea University Anam Hospital, Seoul

138-736

Asan Medical Center, Seoul

143-914

Konkuk University Medical Center, Seoul

SK8 2PX

The Pharmacy Department, Cheadle

SN3 6BB

The Shalbourne Suite, Swindon

SN3 6BW

Kingshill Research Centre, Swindon

M50 2GY

MAC UK Neuroscience Ltd, Manchester

SO16 6YD

Wellcome Trust Clinical Research Facility, Southampton

SO30 3JB

Memory Assessment and Research Centre, Southampton

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT00722046 - Multiple IV Dose Study Of PF-04360365 In Patients With Mild To Moderate Alzheimer's Disease | Biotech Hunter | Biotech Hunter