Study of Carboplatin/Paclitaxel in Combination With ABT-869 in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

PHASE2CompletedINTERVENTIONAL
Enrollment

145

Participants

Timeline

Start Date

June 30, 2008

Primary Completion Date

April 30, 2012

Study Completion Date

April 30, 2012

Conditions
Advanced or Metastatic Non-Small Cell Lung Cancer
Interventions
DRUG

ABT-869

12.5 mg ABT-869

DRUG

Placebo for ABT-869

Placebo Comparator (12.5 mg or 7.5 mg)

DRUG

ABT-869

7.5 mg ABT-869

DRUG

Carboplatin

Carboplatin (AUC 6 mg/mL/min)

DRUG

Paclitaxel

Paclitaxel (200 mg/m2)

Trial Locations (37)

2480

Site Reference ID/Investigator# 21862, Lismore

4870

Site Reference ID/Investigator# 23682, Cairns

5011

Site Reference ID/Investigator# 19043, Woodville South

5042

Site Reference ID/Investigator# 19042, Bedford Park

12808

Site Reference ID/Investigator# 18962, Prague

19106

Site Reference ID/Investigator# 13101, Philadelphia

19107

Site Reference ID/Investigator# 24122, Philadelphia

26995

Site Reference ID/Investigator# 19022, Pribram V

27403

Site Reference ID/Investigator# 15848, Greensboro

30322

Site Reference ID/Investigator# 7179, Atlanta

33136

Site Reference ID/Investigator# 15841, Miami

44195

Site Reference ID/Investigator# 15847, Cleveland

44718

Site Reference ID/Investigator# 22444, Canton

48912

Site Reference ID/Investigator# 15851, Lansing

54769

Site Reference ID/Investigator# 22504, Náchod

69733

Site Reference ID/Investigator# 18964, Kyjov

77520

Site Reference ID/Investigator# 18963, Olomouc

85224

Site Reference ID/Investigator# 15850, Chandler

85381

Site Reference ID/Investigator# 15846, Peoria

115478

Site Reference ID/Investigator# 18064, Moscow

Site Reference ID/Investigator# 18065, Moscow

Site Reference ID/Investigator# 23312, Moscow

119228

Site Reference ID/Investigator# 18961, Singapore

143423

Site Reference ID/Investigator# 18066, Moscow

198255

Site Reference ID/Investigator# 23562, Saint Petersburg

420029

Site Reference ID/Investigator# 38003, Kazan'

610021

Site Reference ID/Investigator# 38260, Kirov

03756

Site Reference ID/Investigator# 15844, Lebanon

07601

Site Reference ID/Investigator# 22443, Hackensack

17033-0850

Site Reference ID/Investigator# 26842, Hershey

17210-120

Site Reference ID/Investigator# 17703, Jaú

90050-170

Site Reference ID/Investigator# 23522, Porto Alegre

90610-000

Site Reference ID/Investigator# 15601, Porto Alegre

20231-050

Site Reference ID/Investigator# 17704, Rio de Janeiro

09060-650

Site Reference ID/Investigator# 22684, Santo André

01224-010

Site Reference ID/Investigator# 17702, São Paulo

04024-002

Site Reference ID/Investigator# 23582, São Paulo

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

AbbVie (prior sponsor, Abbott)

INDUSTRY