Four-period Crossover Study to Assess the Effects of Single Oral Doses of ZD4054 (Zibotentan) (10mg and 30mg) on QTc Interval

PHASE1CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

June 30, 2008

Study Completion Date

November 30, 2008

Conditions
Healthy
Interventions
DRUG

ZD4054

ZD4054 10mg Tablet

DRUG

Moxifloxacin

400 mg capsule

DRUG

ZD4054 Placebo

3 tablets

DRUG

Moxifloxacin placebo

1 capsule

DRUG

ZD4054 Placebo

2 tablets

DRUG

ZD4054

30mg tablet

DRUG

ZD4054

10mg tablet

Trial Locations (1)

Unknown

Research Site, Macclesfield

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY