Dose Response to Topical Glyceryl Trinitrate in Patients With Raynaud's Phenomenon

PHASE1CompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

June 30, 2008

Primary Completion Date

November 30, 2008

Study Completion Date

November 30, 2008

Conditions
Raynaud's Phenomenon
Interventions
DRUG

placebo cream

placebo cream applied to 2 adjacent fingers of non-dominant hand one time

DRUG

Glyceryl Trinitrate

0.6mg of Glyceryl Trinitrate applied to 2 adjacent fingers on non-dominant hand one time

DRUG

Glyceryl Trinitrate

1.2mg Glyceryl Trinitrate topically to 2 adjacent fingers of non-dominant hand one time

DRUG

Glyceryl Trinitrate

1.8mg Glyceryl Trinitrate topically to 2 adjacent fingers of non-dominant hand one time

DRUG

Glyceryl Trinitrate

2.4 mg Glyceryl Trinitrate topically to 2 adjacent fingers of non-dominant hand one time

Trial Locations (1)

52242

University of Iowa-Institute for Clinical and Translational Science, Iowa City

Sponsors
All Listed Sponsors
lead

Procris Pharmaceuticals

INDUSTRY