NCT00700076 - Pilot Study of ORG 25935 Modulation of Ketamine-induced Behavioral and Cognitive Effects in Healthy Male Subjects | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 22, 2008

Primary Completion Date

March 9, 2009

Study Completion Date

March 9, 2009

Conditions

Healthy

Interventions

DRUG

Ketamine and Org 25935

Oral administration of Org 25935 16 mg and intravenous administration of ketamine (0.23 mg/kg bolus over 1 minute, followed by 0.58 mg/kg/hour x 30 minutes, followed by 0.29 mg/kg/hour x 69 minutes)

DRUG

Placebo and Ketamine

Oral administration of placebo and intravenous administration of ketamine (0.23 mg/kg bolus over 1 minute, followed by 0.58 mg/kg/hour x 30 minutes, followed by 0.29 mg/kg/hour x 69 minutes)

Trial Locations (1)

06516

Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine, West Haven