Assess the Effect of Cangrelor at the Therapeutic Dose and a Supratherapeutic Dose Level on the QT/QTc Interval in Healthy Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

June 30, 2008

Primary Completion Date

November 30, 2008

Study Completion Date

November 30, 2008

Conditions
Healthy
Interventions
DRUG

cangrelor

IV bolus 60 mcg/kg; 8 mcg/kg x 3 hrs

DRUG

cangrelor

30 mcg/kg bolus; 4 mcg/kg/min x 3 hrs. Oral placebo capsule

DRUG

cangrelor

60 mcg/kg bolus; 8 mcg/kg/min x 3 hrs. Oral placebo capsule

DRUG

moxifloxacin

400 mg orally. Placebo IV bolus and infusion.

DRUG

placebo

placebo IV and oral

Trial Locations (1)

98418

Charles River Clinical Services NW, Tacoma

Sponsors
All Listed Sponsors
lead

The Medicines Company

INDUSTRY