Study of Gemcitabine and Erlotinib Plus Sorafenib (GES) in Metastatic Pancreatic Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

September 30, 2007

Primary Completion Date

November 30, 2010

Study Completion Date

June 30, 2013

Conditions
Pancreatic Cancer
Interventions
DRUG

Gemcitabine

1000 mg/m\^2, intravenous, Days 1, 8, 15 for every 28-day cycle. In the absence of disease progression or toxicity, a patient may continue to receive gemcitabine, erlotinib, and sorafenib until disease progression.

DRUG

Erlotinib

150 mg, taken orally, once a day, Days 1-28 for every 28-day cycle. In the absence of disease progression or toxicity, a patient may continue to receive gemcitabine, erlotinib, and sorafenib until disease progression.

DRUG

Sorafenib

400 mg, taken orally, twice a day, Days 1-28 for every 28-day cycle. In the absence of disease progression or toxicity, a patient may continue to receive gemcitabine, erlotinib, and sorafenib until disease progression.

Trial Locations (3)

10016

Bellevue Hospital, New York

New York University Cancer Center, New York

92262

Desert Regional Medical Center, Palm Springs

Sponsors

Collaborators (2)

All Listed Sponsors
collaborator

Bayer

INDUSTRY

collaborator

OSI Pharmaceuticals

INDUSTRY

lead

NYU Langone Health

OTHER