NCT00692939 - Autologous Stem Cell Transplantation for Crohn's Disease | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

June 26, 2012

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions

Crohn's Disease

Interventions

BIOLOGICAL

autologous CD34-selected peripheral blood stem cells transplant

high-dose immunotherapy followed by infusion of autologous CD34-selected peripheral blood stem cells (PBSC)

DRUG

Alemtuzumab

Transplant conditioning

DRUG

ATG

Transplant conditioning

DRUG

Melphalan

Transplant conditioning

DRUG

Thiotepa

Transplant conditioning

DRUG

Rituximab

Transplant conditioning

DRUG

Cyclophosphamide

Mobilization

DRUG

G-CSF

Mobilization

DRUG

Mesna

Mobilization

Trial Locations (2)

15213

RECRUITING

UPMC Prebyterian- Adult Gastroenterology, Pittsburgh

15224

RECRUITING

Children's Hospital of Pittsburgh of UPMC-Bone Marrow Team, Pittsburgh

All Listed Sponsors

lead

Paul Szabolcs

OTHER