NCT00688987View on ClinicalTrials.gov

The Hypothalamic-Pituitary-Adrenal (HPA) Axis as an Effector System in Weight Regulation

NACompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

August 31, 2000

Primary Completion Date

July 31, 2004

Study Completion Date

August 31, 2004

Conditions
ObesityAddison's Disease
Interventions
DRUG

Hydrocortisone

Subjects will receive in random order daily (split) dosing of hydrocortisone: a low dose of 15 mg (10 in AM, 5 in PM); a medium dose of 25 mg (15 in AM, 10 in PM) and high dose of 40 mg (30 in AM, 10 in PM) for 4 months.

DIETARY_SUPPLEMENT

Isocaloric Diet

Subjects will eat an isocaloric diet for 4 weeks while taking hydrocortisone

Trial Locations (1)

97239

Oregon Health & Science University, Portland

All Listed Sponsors
lead

Oregon Health and Science University

OTHER

NCT00688987 - The Hypothalamic-Pituitary-Adrenal (HPA) Axis as an Effector System in Weight Regulation | Biotech Hunter | Biotech Hunter