A Double-Blind, Placebo-Controlled Study of Aripiprazole Adjunctive to Antidepressant Therapy

PHASE3CompletedINTERVENTIONAL
Enrollment

225

Participants

Timeline

Start Date

September 30, 2008

Primary Completion Date

September 30, 2009

Study Completion Date

September 30, 2009

Conditions
Major Depressive Disorder
Interventions
DRUG

Aripiprazole 5mg

Tablet dose of aripiprazole will be 2 mg/day during the first phase (30 days) of the study, and 5 mg/day in the second phase (30 days)

DRUG

Aripiprazole 2mg

For patients randomly assigned to the placebo/drug sequence, the dose of aripiprazole will be 2 mg/day during the second phase of the study (30 days)

DRUG

Placebo

for patients randomly assigned to the placebo/placebo sequence, study medication will be placebo during both phases of the study (60 days)

Trial Locations (1)

02114

Massachusetts General Hospital, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Massachusetts General Hospital

OTHER