NCT00683553 - A Dose Escalation and Safety Study of I5NP to Prevent Acute Kidney Injury (AKI) in Patients at High Risk of AKI Undergoing Major Cardiovascular Surgery (QRK.004) | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

May 31, 2008

Primary Completion Date

May 31, 2010

Study Completion Date

September 30, 2010

Conditions

Acute Renal FailureAcute Kidney Injury

Interventions

DRUG

I5NP

Single IV injection of experimental drug given in escalated doses at 0.5, 1.5, 5.0 and 10 mg/kg doses to different patients

DRUG

Placebo

Single IV injection of saline

Trial Locations (10)

University of Pittsburgh Medical Center, Pittsburgh

George Washington University, Washington D.C.

University of Alabama at Birmingham, Birmingham

Cleveland Clinic Foundation, Cleveland

Washington University, St Louis

Texas Heart Institute, Houston

The Methodist Hospital, Houston

University of Texas, Houston

Mayo Clinic Hospital, Phoenix

University of Virginia School of Medicine, Charlottesville