Positron Emission Tomography (PET) Study With (11C) Flumazenil to Determine Central GABAA Receptor Occupancy of AZD6280

PHASE1CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

February 29, 2008

Primary Completion Date

September 30, 2008

Study Completion Date

September 30, 2008

Conditions
Anxiety
Interventions
DRUG

AZD6280

Single dose of oral solution or capsule(s). 3 times for the 2 subjects in Panel 1. Once for the 6 remaining subjects.

DRUG

(11C) flumazenil

Single dose of intravenous solution. 4 times for 2 subjects in Panel 1. 2 times for the remaining 6 subjects. (once together with AZD6280)

Trial Locations (1)

Unknown

Research Site, Stockholm

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY