Safety and Efficacy Study of 4975 in Patients Undergoing Total Knee Replacement

PHASE3CompletedINTERVENTIONAL
Enrollment

214

Participants

Timeline

Start Date

September 30, 2007

Primary Completion Date

September 30, 2008

Study Completion Date

December 31, 2008

Conditions
Total Knee Arthroplasty (Replacement)
Interventions
DRUG

4975, 15 and 5 mg

Direct instillation into the surgical site

DRUG

Placebo Comparator

Direct instillation into the surgical site

DRUG

4975 - 5 mg

Direct instillation into the surgical site

Trial Locations (25)

15143

Sewickley Valley Hospital, Sewickley

19140

Temple University Hospital, Philadelphia

21204

Ruxton Professional Center - Orthopaedic Associates, Towson

32127

Coastal Medical Research, Port Orange

32720

Florida Hospital - Florida Research Associates, LLC, DeLand

32804

Southeastern Clinical Research Consultants, Orlando

33136

University of Miami, Miller School of Medicine, Miami

33186

Miami Institute for Medical Research, Miami

35235

Alabama Clinical Therapeutics, LLC, Birmingham

35660

Hellen Keller Hospital, Sheffield

36608

Springhill Medical Center, Mobile

44195

Cleveland Clinic, Cleveland

48085

William Beaumont Hospital, Royal Oak

William Beaumont Hospital, Troy

60612

Rush University Medical Center, Chicago

75231

Presbyterian Hospital of Dallas, Dallas

77024

Memorial City Hospital - Memorial Hermann Healthcare System, Houston

85712

Visions Clinical Research/Tucson Medical Center, Tucson

91206

Glendale Adventist Medical Center - Lotus Clinical Research, Glendale

92653

Physicians Clinical Research Corporation, Laguna Hills

Saddleback Memorial Medical Center/Accurate Clinical Trials, Laguna Hills

94115

UCSF-Mt. Zion Medical Center, San Francisco

94612

Webster Orthopeadic Medical Group, Oakland

97239

Oregon Health & Science University, Portland

06106

Orthopedic Associates of Hartford, Hartford

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Anesiva, Inc.

INDUSTRY

NCT00681356 - Safety and Efficacy Study of 4975 in Patients Undergoing Total Knee Replacement | Biotech Hunter | Biotech Hunter