Evaluating The Safety Of Donepezil Hydrochloride (Aricept) For Up To 1 Year In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome - Follow-Up To A 10-Week, Double-Blind, Placebo-Controlled Trial

PHASE2TerminatedINTERVENTIONAL
Enrollment

117

Participants

Timeline

Start Date

April 4, 2008

Primary Completion Date

November 13, 2008

Study Completion Date

December 15, 2008

Conditions
Down Syndrome
Interventions
DRUG

Donepezil hydrochloride (Aricept)

Liquid form Aricept - 5 mg/5 mL donepezil hydrochloride.

Trial Locations (31)

27710

Division of Genetics and Developmental Behavior, Durham

29425

Medical Univ of South Carolina, Charleston

30342

Road Runner Research, Atlanta

33155

Miami Children's Hospital - Medical Genetics and Neuro-Developmental Center, Miami

Phoenix Children's Hospital, Miami

33407

Northwest Clinical Research Center, West Palm Beach

33709

Clinical Studies Centers, LLC, St. Petersburg

33912

Neufeld Medical Group, Inc., Fort Myers

43606

Valko and Associates, Toledo

44109

Metrohealth Medical Center, Cleveland

48503

Hurley Medical Center, Flint

49503

Saint Mary's Health Care, Grand Rapids

Washington University School of Medicine, Grand Rapids

63110

Northwest Clinical Research Center, St Louis

68504

Meridien Research, Lincoln

72205

Child Neurology Associates, PC, Little Rock

74104

Office of Lazlo Mate, Tulsa

77030

Down Syndrome Clinic of Houston, Houston

78258

Alamo City Clinical Research, LLC, San Antonio

Community Research Foundation, San Antonio

80214

Rocky Mountain Pediatrics, P.C., Lakewood

85016

Phoenix Children's Hospital, Phoenix

90048

Midwest Children's Health Research Institute, Los Angeles

92123

UCSD Pediatric Pharmacology Research Unit, San Diego

92868

University of California, Irvine Medical Center, Orange

94609

Children's Hospital and Research Center at Oakland, Oakland

98004

Neuropsychiatric Research Center of Southwest Florida, Bellevue

33155-3009

Miami Children's Hospital, Miami

55101-2595

Regions Hospital, Saint Paul

08043

Clinical Research Center of New Jersey, Voorhees Township

37232-9225

Vanderbilt Children's Hospital, Nashville

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

lead

Eisai Inc.

INDUSTRY

NCT00675025 - Evaluating The Safety Of Donepezil Hydrochloride (Aricept) For Up To 1 Year In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome - Follow-Up To A 10-Week, Double-Blind, Placebo-Controlled Trial | Biotech Hunter | Biotech Hunter