Cardio Risk of Acute Schizophrenia Olanzapine Duke

PHASE4WithdrawnINTERVENTIONAL
0
Timeline

Start Date

April 30, 2008

Primary Completion Date

December 31, 2009

Study Completion Date

February 28, 2010

Conditions
SchizophreniaSchizoaffective Disorder
Interventions
DRUG

Olanzapine

Olanzapine zydis 15 mg QHS for 28 days

DRUG

Metformin

Metformin capsules will be started at 500 mg twice a day (before breakfast and before dinner) for days 1-3, then 500 mg before breakfast and 1000 mg before dinner for days 4-7, and then 1000 mg twice a day thereafter.

DRUG

Simvastatin

Simvastatin will be started at 10 mg at bed time for the first week and 20 mg at bedtime thereafter.

Trial Locations (2)

27509

John Umstead Hospital, Butner

27705

Duke University Medical Center, Durham

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Duke University

OTHER

NCT00672464 - Cardio Risk of Acute Schizophrenia Olanzapine Duke | Biotech Hunter | Biotech Hunter