NCT00666354 - Dose Response and Safety Study of Topical Methotrexate for the Treatment of Fingernail Psoriasis | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

October 31, 2007

Primary Completion Date

September 30, 2008

Study Completion Date

January 31, 2009

Conditions

Fingernail Psoriasis

Interventions

DRUG

Methotrexate

0.01 gram of topical amphimatrix containing 0.05% methotrexate per affected nail and adjacent skin folds applied daily for three months.

DRUG

Methotrexate

0.01 gram of topical amphimatrix containing 0.25% methotrexate per affected nail and adjacent skin folds applied daily for three months.

DRUG

Methotrexate

0.01 gram of topical amphimatrix containing 1.0% methotrexate per affected nail and adjacent skin folds applied daily for three months.

Trial Locations (7)

University of Manchester, The Dermatology Centre, Salford

Great Western Hospital Rheumatology Department, Swindon

Aberdeen Royal Infirmary Dermatology Outpatients Clinic, Aberdeen

Royal National Hospital for Rheumatic Diseases, Bath

University Hospital of Wales, Welsh Institute of Dermatology, Cardiff

Leeds General Infirmary Department of Dermatology, Leeds

George Eliot Hospital, Department of Dermatology, Nuneaton