Evaluating the Safety and Effectiveness of Decitabine in People With Thalassemia Intermedia

PHASE2CompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

January 31, 2008

Primary Completion Date

May 31, 2010

Study Completion Date

September 30, 2010

Conditions
Thalassemia
Interventions
DRUG

Decitabine (USAN, INN)

Participants will receive 0.2 mg/kg of decitabine subcutaneously twice a week for 12 weeks. The dose will be reduced for toxicities as needed. The maximum dose of decitabine to be given will be 0.2 mg/kg.

Trial Locations (3)

19104

Children's Hospital Philadelphia, Philadelphia

94609

Children's Hospital and Research Center at Oakland, Oakland

M5G 2C4

University Health Network, Toronto

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Carelon Research

OTHER