A Randomized, Double-Blind Study of the Efficacy and Safety of Valdecoxib Compared to Placebo for Treatment of Post- Cholecystectomy Surgery Pain

PHASE3CompletedINTERVENTIONAL
Enrollment

490

Participants

Timeline

Start Date

November 30, 2002

Study Completion Date

July 31, 2003

Conditions
Laparoscopic CholecystectomyPain
Interventions
DRUG

placebo

valdecoxib 40 mg by mouth within 8 hours after the end of surgery, followed by a second dose of valdecoxib 20 mg within 1 to 12 hours (or by midnight on the Day 1, whichever was earlier); then, placebo twice daily (BID) on Days 2 to 5

DRUG

valdecoxib

valdecoxib 40 mg by mouth within 8 hours after the end of surgery, followed by a second dose of valdecoxib 20 mg within 1 to 12 hours (or by midnight on the Day 1, whichever was earlier); then, valdecoxib 20 mg once daily (QD)on Days 2 to 5.

DRUG

valdecoxib

valdecoxib 40 mg by mouth within 8 hours after the end of surgery, followed by a second dose of valdecoxib 20 mg within 1 to 12 hours (or by midnight on the Day 1, whichever was earlier); then, valdecoxib 20 mg twice daily (BID) on Days 2 to 5.

Trial Locations (65)

15212

Pfizer Investigational Site, Pittsburgh

18103

Pfizer Investigational Site, Allentown

20850

Pfizer Investigational Site, Rockville

20874

Pfizer Investigational Site, Germantown

20902

Pfizer Investigational Site, Silver Spring

21229

Pfizer Investigational Site, Baltimore

23434

Pfizer Investigational Site, Suffolk

23517

Pfizer Investigational Site, Norfolk

27103

Pfizer Investigational Site, Winston-Salem

27710

Pfizer Investigational Site, Durham

29203

Pfizer Investigational Site, Columbia

29209

Pfizer Investigational Site, Columbia

29406

Pfizer Investigational Site, Charleston

Pfizer Investigational Site, North Charleston

29464

Pfizer Investigational Site, Mt. Pleasant

29485

Pfizer Investigational Site, Summerville

30060

Pfizer Investigational Site, Marietta

30513

Pfizer Investigational Site, Blue Ridge

32504

Pfizer Investigational Site, Pensacola

33136

Pfizer Investigational Site, Miami

33176

Pfizer Investigational Site, Miami

35213

Pfizer Investigational Site, Birmingham

35660

Pfizer Investigational Site, Sheffield

36526

Pfizer Investigational Site, Daphne

36532

Pfizer Investigational Site, Fairhope

36617

Pfizer Investigational Site, Mobile

36693

Pfizer Investigational Site, Mobile

37620

Pfizer Investigational Site, Bristol

37660

Pfizer Investigational Site, Kingsport

39202

Pfizer Investigational Site, Jackson

52242

Pfizer Investigational Site, Iowa City

53792

Pfizer Investigational Site, Madison

60153

Pfizer Investigational Site, Maywood

60611

Pfizer Investigational Site, Chicago

71105

Pfizer Investigational Site, Shreveport

73104

Pfizer Investigational Site, Oklahoma City

77024

Pfizer Investigational Site, Houston

77055

Pfizer Investigational Site, Houston

78148

Pfizer Investigational Site, Universal City

78224

Pfizer Investigational Site, San Antonio

84070

Pfizer Investigational Site, Sandy City

84088

Pfizer Investigational Site, West Jordan

84094

Pfizer Investigational Site, Sandy City

85006

Pfizer Investigational Site, Phoenix

85020

Pfizer Investigational Site, Phoenix

85023

Pfizer Investigational Site, Phoenix

85027

Pfizer Investigational Site, Phoenix

85306

Pfizer Investigational Site, Glendale

85308

Pfizer Investigational Site, Glendale

85710

Pfizer Investigational Site, Tucson

85711

Pfizer Investigational Site, Tucson

85712

Pfizer Investigational Site, Tucson

90017

Pfizer Investigational Site, Los Angeles

90057

Pfizer Investigational Site, Los Angeles

91109

Pfizer Investigational Site, Pasadena

92801

Pfizer Investigational Site, Anaheim

93309

Pfizer Investigational Site, Bakersfield

93311

Pfizer Investigational Site, Bakersfield

95124

Pfizer Investigational Site, San Jose

95695

Pfizer Investigational Site, Woodland

95817

Pfizer Investigational Site, Sacramento

98055

Pfizer Investigational Site, Renton

27103-3315

Pfizer Investigational Site, Winston-Salem

19107-4998

Pfizer Investigational Site, Philadelphia

98058-5010

Pfizer Investigational Site, Renton

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY

NCT00661635 - A Randomized, Double-Blind Study of the Efficacy and Safety of Valdecoxib Compared to Placebo for Treatment of Post- Cholecystectomy Surgery Pain | Biotech Hunter | Biotech Hunter