Open Label Phase II Study of BAY 43-9006 in Chronic Myelogenous Leukemia (CML) Patients Resistant to Gleevec

PHASE2CompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

January 31, 2004

Primary Completion Date

February 28, 2005

Study Completion Date

February 28, 2005

Conditions
Chronic Myelogenous Leukemia
Interventions
DRUG

Nexavar (Sorafenib, BAY43-9006)

Patients will receive Bay 43-9006 400 mg po twice daily in a continuous, uninterrupted schedule. Treatment will continue until there is objective evidence of disease progression, or until evidence of toxicities that are unacceptable and thought to be related to study drug, which requires discontinuation of drug, or due to withdrawn patient consent.

Trial Locations (4)

69437

Lyon

75010

Paris

86021

Poitiers

97239

Portland

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Bayer

INDUSTRY