Comparison of Crinone 8% Intravaginal Gel and IM Progesterone Supplementation for In Vitro Fertilization (IVF)

PHASE4CompletedINTERVENTIONAL
Enrollment

468

Participants

Timeline

Start Date

July 31, 2003

Primary Completion Date

November 30, 2008

Study Completion Date

July 31, 2009

Conditions
Infertility
Interventions
DRUG

Crinone 8% Vaginal Gel

Crinone 8% (90 mg of micronized progesterone in a bioadhesive vaginal gel contained in a single use, one piece applicator) once a day beginning the second day following oocyte retrieval (Study Group A) continuing until the pregnancy test is negative or until the 10th week of pregnancy.

DRUG

Intramuscular Progesterone

Progesterone-50 mg intramuscularly once a day beginning the day after oocyte retrieval continuing until the pregnancy test is negative or if positive, switching to Crinone 8% intravaginal gel until the 10th week of pregnancy.

Trial Locations (1)

02115

Brigham and Women's Hospital, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

EMD Serono

INDUSTRY

lead

Brigham and Women's Hospital

OTHER

NCT00656201 - Comparison of Crinone 8% Intravaginal Gel and IM Progesterone Supplementation for In Vitro Fertilization (IVF) | Biotech Hunter | Biotech Hunter