A Study to Evaluate the Efficacy and Safety of Quinapril or Quinapril Plus Hydrochlorothiazide in Patients With Mild to Moderate Hypertension

PHASE4CompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

December 31, 2002

Study Completion Date

June 30, 2004

Conditions
Hypertension
Interventions
DRUG

quinapril 20 mg

Quinapril 20 mg oral tablet daily for the first 6 weeks, and if a responder, continued on quinapril 20 mg for an additional 6 weeks

DRUG

quinapril 20 mg plus hydrochlorothiazide 12.5 mg

Quinapril 20 mg oral tablet daily for the first 6 weeks; if nonresponder, could be randomized to quinapril 20 mg plus hydrochlorothiazde 12.5 mg daily (Accuzide tablets) for 6 weeks

DRUG

quinapril 40 mg

Quinapril 20 mg oral tablet daily for the first 6 weeks; if nonresponder, could be randomized to quinapril 40 mg oral tablet daily for 6 weeks

Trial Locations (3)

21280

Pfizer Investigational Site, Diyarbak R

34300

Pfizer Investigational Site, Cerrahpaşa

Unknown

Pfizer Investigational Site

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY