A Study of the Antiplatelet Effects Comparing Ticagrelor (Ticag. - AZD6140) With Clopidogrel (Clop.) Responder and Non-responders

PHASE2CompletedINTERVENTIONAL
Enrollment

98

Participants

Timeline

Start Date

May 31, 2008

Primary Completion Date

March 31, 2009

Study Completion Date

March 31, 2009

Conditions
Stable Coronary Artery Disease
Interventions
DRUG

Ticagrelor

Tablets, Oral, 90 mg; 180 mg loading dose followed by 90 mg twice daily for 2 weeks

DRUG

Clopidogrel

(over encapsulated) capsule, Oral, 75 mg; 600 mg loading dose followed by 75 mg once daily for 2 weeks

DRUG

Aspirin

Tablets, Oral, 75 mg to 100 mg once daily. Aspirin obtained locally by the investigator, according to local practice. The dose remained constant throughout the study

Trial Locations (10)

Unknown

Research Site, Jonesboro

Research Site, Ormond Beach

Research Site, Baltimore

Research Site, Cincinnati

Research Site, Hamilton

Research Site, Lachine

Research Site, Aalborg

Research Site, Aarhus

Research Site, Esbjerg

Research Site, Sheffield

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY