Single Dose Study in Patients With Chronic Obstructive Pulmonary Disease (COPD) Associated Pulmonary Hypertension.

PHASE1CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

August 31, 2008

Primary Completion Date

September 30, 2009

Study Completion Date

September 30, 2009

Conditions
Hypertension, PulmonaryPulmonary Disease, Chronic Obstructive
Interventions
DRUG

Riociguat (Adempas, BAY63-2521) 1.0 mg

1.0 mg BAY63-2521 will be given twice per subject, as single dose administration during the hemodynamic investigation (on study day 1) and during the lung function testing (on study day 3).

DRUG

Riociguat (Adempas, BAY63-2521) 2.5 mg

2.5 mg BAY63-2521 will be given twice per subject, as single dose administration during the hemodynamic investigation (on study day 1) and during the lung function testing (on study day 3).

Trial Locations (7)

17475

Greifswald

35392

Giessen

61231

Bad Nauheim

69126

Heidelberg

74245

Löwenstein

81377

München

01307

Dresden

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Bayer

INDUSTRY

NCT00640315 - Single Dose Study in Patients With Chronic Obstructive Pulmonary Disease (COPD) Associated Pulmonary Hypertension. | Biotech Hunter | Biotech Hunter