40
Participants
Start Date
February 28, 2010
Primary Completion Date
July 31, 2013
Study Completion Date
January 31, 2014
RAD001(Everolimus)
In this study, 5-azacitidine will be administered sc for 7 doses over 9 days in a 28 day cycle. Everolimus will be administered orally with the first dose starting on day 5 (first Friday) of each cycle and continued until day 21 of each cycle. Patients will be treated with combined azacitidine + Everolimus for a minimum of 6 cycles and until at least 2 cycles after documentation of CR. Upon cessation of azacitidine, the patient will be permitted to take Everolimus maintenance therapy until progression at the investigator's discretion.
BaysideHealth, The Alfred Hospital, Melbourne
Lead Sponsor
Bayside Health
OTHER_GOV