Rituximab, Lenalidomide, and Bortezomib in Mantle Cell Lymphoma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

June 30, 2008

Primary Completion Date

April 30, 2015

Study Completion Date

November 30, 2016

Conditions
Mantle Cell Lymphoma
Interventions
DRUG

Rituximab

"DL 1, DL 2, and DL 3: 375 mg/m2 IV Days 1, 8, and 15; Cycles 2-6: 375 mg/m2 IV Day 1~Same for DL-1."

DRUG

Bortezomib

"DL 1, DL 2, and DL 3: 1.3 mg/m2 IV Days 1, 4, 8, and 11~Same for DL-1."

DRUG

Lenalidomide

"DL 1: 15 mg PO daily Days 1-14 followed by 7 days of rest~DL 2: 20 mg PO daily Days 1-14 followed by 7 days of rest~DL 3: 25 mg PO daily Days 1-14 followed by 7 days of rest~DL-1: 10 mg PO daily Days 1-14 followed by 7 days of rest"

Trial Locations (7)

37023

Tennessee Oncology, PLLC, Nashville

37404

Chattanooga Oncology Hematology Associates, Chattanooga

45242

Oncology Hematology Care Inc., Cincinnati

47802

Providence Medical Group, Terre Haute

RHHP/ Hope Cancer Center, Terre Haute

63017

St. Louis Cancer Care, Chesterfield

07960

Hematology-Oncology Associates of Northern NJ, Morristown

All Listed Sponsors
collaborator

Millennium Pharmaceuticals, Inc.

INDUSTRY

collaborator

Celgene

INDUSTRY

lead

SCRI Development Innovations, LLC

OTHER

NCT00633594 - Rituximab, Lenalidomide, and Bortezomib in Mantle Cell Lymphoma | Biotech Hunter | Biotech Hunter