A Study of Recombinant Vaccinia Virus to Evaluate the Safety and Efficacy of a Transdermal Injection Within the Tumor of Patients With Primary or Metastatic Hepatic Carcinoma

PHASE1CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

July 31, 2007

Study Completion Date

August 31, 2007

Conditions
Neoplasms, Liver
Interventions
GENETIC

JX-594: Recombinant vaccinia virus (TK-deletion plus GM-CSF)

The total dose is divided between 1-3 tumors located within the liver. Patients are treated with JX-594 once every 3 weeks until progression at the site(s) of injection or until the patient has received a maximum of 4 treatments.

Trial Locations (1)

602-715

Dong-A University Hospital, Busan

Sponsors
All Listed Sponsors
collaborator

Green Cross Corporation

INDUSTRY

lead

Jennerex Biotherapeutics

INDUSTRY