NCT00628264 - Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac Surgery | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

March 31, 2008

Primary Completion Date

June 30, 2009

Study Completion Date

June 30, 2009

Conditions

Cardiac SurgeryCoronary Artery Bypass GraftingValve SurgeryKidney Injury

Interventions

DRUG

AP214

Three AP214 bolus infusions administered over 10 minutes (prior to skin incision, at time of clamp-release and 6 hours after clamp-release).

DRUG

Placebo

Three placebo bolus infusions administered over 10 minutes (prior to skin incision, at time of clamp-release and 6 hours after clamp-release).

Trial Locations (2)

Shands Hospital at Alachua General Hospital, Gainesville

Shands Hopsital at University of Florida, Gainesville